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Neutrophil cerebrovascular transmigration triggers rapid neurotoxicity through release of proteases associated with de-condensed DNA

Cerebrovascular inflammation contributes to diverse central nervous system (CNS) disorders through mechanisms that are incompletely understood. The recruitment of neutrophils to the brain can contribute to neurotoxicity, particularly during acute brain injuries such as cerebral ischaemia, trauma and...

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Autors principals: Allen, Charlotte, Thornton, Peter, Denes, Adam, McColl, Barry W., Pierozynski, Adam, Monestier, Marc, Pinteaux, Emmanuel, Rothwell, Nancy J., Allan, Stuart M.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3381844/
https://ncbi.nlm.nih.gov/pubmed/22661091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200409
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