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DNA Damage Response Pathway and Replication Fork Stress During Oligonucleotide Directed Gene Editing

Single-stranded DNA oligonucleotides (ODNs) can be used to direct the exchange of nucleotides in the genome of mammalian cells in a process known as gene editing. Once refined, gene editing should become a viable option for gene therapy and molecular medicine. Gene editing is regulated by a number o...

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Bibliografski detalji
Glavni autori: Bonner, Melissa, Strouse, Bryan, Applegate, Mindy, Livingston, Paula, Kmiec, Eric B
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3381643/
https://ncbi.nlm.nih.gov/pubmed/23343929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2012.9
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