Antisense Oligonucleotide (AON)-based Therapy for Leber Congenital Amaurosis Caused by a Frequent Mutation in CEP290

Leber congenital amaurosis (LCA) is the most severe form of inherited retinal degeneration, with an onset in the first year of life. The most frequent mutation that causes LCA, present in at least 10% of individuals with LCA from North-American and Northern-European descent, is an intronic mutation...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Collin, Rob WJ, den Hollander, Anneke I, van der Velde-Visser, Saskia D, Bennicelli, Jeannette, Bennett, Jean, Cremers, Frans PM
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2012
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3381589/
https://ncbi.nlm.nih.gov/pubmed/23343883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2012.3
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker