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M channel enhancers and physiological M channel block

NON-TECHNICAL SUMMARY: Specific membrane proteins called ‘M channels’ control the excitability of peripheral pain-sensing nerves. In certain disease conditions (e.g. inflammation), M channels become inhibited, and this contributes to the increased excitability of these nerves and, ultimately, to pai...

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Autors principals: Linley, John E, Pettinger, Louisa, Huang, Dongyang, Gamper, Nikita
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3381311/
https://ncbi.nlm.nih.gov/pubmed/22155935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2011.223404
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