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Structural, Energetic, and Mechanical Perturbations in Rhodopsin Mutant That Causes Congenital Stationary Night Blindness

Several point mutations in rhodopsin cause retinal diseases including congenital stationary night blindness and retinitis pigmentosa. The mechanism by which a single amino acid residue substitution leads to dysfunction is poorly understood at the molecular level. A G90D point mutation in rhodopsin c...

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Detalhes bibliográficos
Main Authors: Kawamura, Shiho, Colozo, Alejandro T., Ge, Lin, Müller, Daniel J., Park, Paul S.-H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3381145/
https://ncbi.nlm.nih.gov/pubmed/22549882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.340182
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