N-Glycosylation Determines Ionic Permeability and Desensitization of the TRPV1 Capsaicin Receptor

The balance of glycosylation and deglycosylation of ion channels can markedly influence their function and regulation. However, the functional importance of glycosylation of the TRPV1 receptor, a key sensor of pain-sensing nerves, is not well understood, and whether TRPV1 is glycosylated in neurons...

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Bibliografiset tiedot
Päätekijät: Veldhuis, Nicholas A., Lew, Michael J., Abogadie, Fe C., Poole, Daniel P., Jennings, Ernest A., Ivanusic, Jason J., Eilers, Helge, Bunnett, Nigel W., McIntyre, Peter
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2012
Aiheet:
Glycobiology and Extracellular Matrices
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3381139/
https://ncbi.nlm.nih.gov/pubmed/22570472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.342022
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