Loss of Mammal-specific Tectorial Membrane Component Carcinoembryonic Antigen Cell Adhesion Molecule 16 (CEACAM16) Leads to Hearing Impairment at Low and High Frequencies

The vertebrate-restricted carcinoembryonic antigen gene family evolves extremely rapidly. Among their widely expressed members, the mammal-specific, secreted CEACAM16 is exceptionally well conserved and specifically expressed in the inner ear. To elucidate a potential auditory function, we inactivat...

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Hlavní autoři: Kammerer, Robert, Rüttiger, Lukas, Riesenberg, Rainer, Schäuble, Constanze, Krupar, Rosemarie, Kamp, Annegret, Sunami, Kishiko, Eisenried, Andreas, Hennenberg, Martin, Grunert, Fritz, Bress, Andreas, Battaglia, Sebastiano, Schrewe, Heinrich, Knipper, Marlies, Schneider, Marlon R., Zimmermann, Wolfgang
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
Témata:
Molecular Bases of Disease
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3381124/
https://ncbi.nlm.nih.gov/pubmed/22544735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.320481
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