Persistence Length of Human Cardiac α-Tropomyosin Measured by Single Molecule Direct Probe Microscopy

α-Tropomyosin (αTm) is the predominant tropomyosin isoform in adult human heart and constitutes a major component in Ca(2+)-regulated systolic contraction of cardiac muscle. We present here the first direct probe images of WT human cardiac αTm by atomic force microscopy, and quantify its mechanical...

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Bibliographic Details
Main Authors: Loong, Campion K. P., Zhou, Huan-Xiang, Chase, P. Bryant
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380901/
https://ncbi.nlm.nih.gov/pubmed/22737252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039676
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