Alpha-Synuclein Cell-to-Cell Transfer and Seeding in Grafted Dopaminergic Neurons In Vivo

Several people with Parkinson’s disease have been treated with intrastriatal grafts of fetal dopaminergic neurons. Following autopsy, 10–22 years after surgery, some of the grafted neurons contained Lewy bodies similar to those observed in the host brain. Numerous studies have attempted to explain t...

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Autors principals: Angot, Elodie, Steiner, Jennifer A., Lema Tomé, Carla M., Ekström, Peter, Mattsson, Bengt, Björklund, Anders, Brundin, Patrik
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380846/
https://ncbi.nlm.nih.gov/pubmed/22737239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039465
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