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Investigating photoexcitation-induced mitochondrial damage by chemotherapeutic corroles using multimode optical imaging

We recently reported that a targeted, brightly fluorescent gallium corrole (HerGa) is highly effective for breast tumor detection and treatment. Unlike structurally similar porphryins, HerGa exhibits tumor-targeted toxicity without the need for photoexcitation. We have now examined whether photoexci...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hwang, Jae Youn, Lubow, David J., Sims, Jessica D., Gray, Harry B., Mahammed, Atif, Gross, Zeev, Medina-Kauwe, Lali K., Farkas, Daniel L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society of Photo-Optical Instrumentation Engineers 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380813/
https://ncbi.nlm.nih.gov/pubmed/22352647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1117/1.JBO.17.1.015003
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