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Photoexcitation of tumor-targeted corroles induces singlet oxygen-mediated augmentation of cytotoxicity

The tumor-targeted corrole particle, HerGa, displays preferential toxicity to tumors in vivo and can be tracked via fluorescence for simultaneous detection, imaging, and treatment. We have recently uncovered an additional feature of HerGa in that its cytotoxicity is enhanced by light irradiation. In...

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Detalhes bibliográficos
Main Authors: Hwang, Jae Youn, Lubow, David J., Chu, David, Sims, Jessica, Alonso-Valenteen, Felix, Gray, Harry B., Gross, Zeev, Farkas, Daniel L., Medina-Kauwe, Lali K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3498762/
https://ncbi.nlm.nih.gov/pubmed/23041277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2012.09.015
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