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On the presence and role of human gene-body DNA methylation

DNA methylation of promoter sequences is a repressive epigenetic mark that down-regulates gene expression. However, DNA methylation is more prevalent within gene-bodies than seen for promoters, and gene-body methylation has been observed to be positively correlated with gene expression levels. This...

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Detalhes bibliográficos
Main Authors: Jjingo, Daudi, Conley, Andrew B., Yi, Soojin V., Lunyak, Victoria V., Jordan, I. King
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380580/
https://ncbi.nlm.nih.gov/pubmed/22577155
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