Aggressiveness of human melanoma xenograft models is promoted by aneuploidy-driven gene expression deregulation

Melanoma is a devastating skin cancer characterized by distinct biological subtypes. Besides frequent mutations in growth- and survival-promoting genes like BRAF and NRAS, melanomas additionally harbor complex non-random genomic alterations. Using an integrative approach, we have analysed genomic an...

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Main Authors: Mathieu, Véronique, Pirker, Christine, Schmidt, Wolfgang M., Spiegl-Kreinecker, Sabine, Lötsch, Daniela, Heffeter, Petra, Hegedus, Balazs, Grusch, Michael, Kiss, Robert, Berger, Walter
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2012
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380575/
https://ncbi.nlm.nih.gov/pubmed/22535842
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