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Synthesis, gp120 binding and anti-HIV activity of fatty acid esters of 1,1-linked disaccharides

Inspired by the anti-human immunodeficiency virus (HIV) activity of analogues of β-galactosylceramide (GalCer), a set of mono- and di- saccharide fatty acid esters were designed as GalCer mimetics and their binding to the V3 loop peptide of HIV-1 and anti-HIV activity evaluated. 1,1-linked Gal-Man a...

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Main Authors: Bachan, Stewart, Fantini, Jacques, Joshi, AnJali, Garg, Himanshu, Mootoo, David R.
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380439/
https://ncbi.nlm.nih.gov/pubmed/21783371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2011.06.078
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