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Regulatory T cells control the CD8 adaptive immune response at the time of ductal obstruction in experimental biliary atresia
CD8 T-lymphocytes are effector cells of cholangiocyte injury in human and in rhesus rotavirus (RRV) induced experimental biliary atresia (BA). Here, we hypothesize that neonatal deficiency in CD25(+)CD4(+) regulatory T cells (Tregs) leads to aberrant activation of hepatic T-lymphocytes in BA. We fou...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3380144/ https://ncbi.nlm.nih.gov/pubmed/22334397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.25662 |
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