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Quantitative comparison of immunohistochemical staining measured by digital image analysis versus pathologist visual scoring

ABSTRACT: Immunohistochemical (IHC) assays performed on formalin-fixed paraffin-embedded (FFPE) tissue sections traditionally have been semi-quantified by pathologist visual scoring of staining. IHC is useful for validating biomarkers discovered through genomics methods as large clinical repositorie...

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Detalhes bibliográficos
Main Authors: Rizzardi, Anthony E, Johnson, Arthur T, Vogel, Rachel Isaksson, Pambuccian, Stefan E, Henriksen, Jonathan, Skubitz, Amy PN, Metzger, Gregory J, Schmechel, Stephen C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3379953/
https://ncbi.nlm.nih.gov/pubmed/22515559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1746-1596-7-42
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