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Development of Multigene Expression Signature Maps at the Protein Level from Digitized Immunohistochemistry Slides

Molecular classification of diseases based on multigene expression signatures is increasingly used for diagnosis, prognosis, and prediction of response to therapy. Immunohistochemistry (IHC) is an optimal method for validating expression signatures obtained using high-throughput genomics techniques...

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Detalhes bibliográficos
Main Authors: Metzger, Gregory J., Dankbar, Stephen C., Henriksen, Jonathan, Rizzardi, Anthony E., Rosener, Nikolaus K., Schmechel, Stephen C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3305321/
https://ncbi.nlm.nih.gov/pubmed/22438942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033520
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