CCR5 Plays a Critical Role in Obesity-Induced Adipose Tissue Inflammation and Insulin Resistance by Regulating Both Macrophage Recruitment and M1/M2 Status

C-C motif chemokine receptor (CCR)2 and its ligand, monocyte chemoattractant protein (MCP)-1, are pivotal for adipose tissue macrophage (ATM) recruitment and the development of insulin resistance. However, other chemokine systems also may play a role in these processes. In this study, we investigate...

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Bibliographic Details
Main Authors: Kitade, Hironori, Sawamoto, Kazuki, Nagashimada, Mayumi, Inoue, Hiroshi, Yamamoto, Yasuhiko, Sai, Yoshimichi, Takamura, Toshinari, Yamamoto, Hiroshi, Miyamoto, Ken-ichi, Ginsberg, Henry N., Mukaida, Naofumi, Kaneko, Shuichi, Ota, Tsuguhito
Format: Artigo
Language:Inglês
Published: American Diabetes Association 2012
Subjects:
Obesity Studies
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3379680/
https://ncbi.nlm.nih.gov/pubmed/22474027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-1506
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