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Regulation of IKKε Expression by Akt2 Isoform

The inhibitor of κ B kinase-ε (IKKε), a breast cancer oncogene, functions as a transforming kinase by activating NF-κB. IKKε is often elevated in breast cancers in the absence of any gene amplification. Because Akt-mediated transformation was shown to require IKKε, we examined if Akt regulates IKKε...

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Detalhes bibliográficos
Main Authors: Krishnamurthy, Soumya, Basu, Alakananda
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3379568/
https://ncbi.nlm.nih.gov/pubmed/22737270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601912444604
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