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Moloney murine leukemia virus genomic RNA packaged in the absence of a full complement of wild type nucleocapsid protein

The current model for MLV genomic RNA (gRNA) packaging predicts that of the thousands of Gag proteins in a budding virion, only a small number (≤1%) may be necessary to recruit gRNA. Here, we examined the threshold limits of functional Gag required to package gRNA using wild-type (WT) and packaging...

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Autors principals: Johnson, Silas F., Garcia, Eric L., Summers, Michael F., Telesnitsky, Alice
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3379553/
https://ncbi.nlm.nih.gov/pubmed/22633243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2012.05.003
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