Memantine treatment decreases levels of secreted Alzheimer’s amyloid precursor protein (APP) and amyloid beta (Aβ) peptide in the human neuroblastoma cells

Memantine, an uncompetitive NMDA receptor antagonist, is a FDA approved drug used for the treatment of moderate to severe Alzheimer’s disease (AD). Several studies have documented protective roles of memantine against amyloid beta peptide (Aβ)(–) mediated damage to neurons in both in vitro and in vi...

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Bibliografiska uppgifter
Huvudupphovsmän: Ray, Balmiki, Banerjee, Pradeep K., Greig, Nigel H., Lahiri, Debomoy K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3379543/
https://ncbi.nlm.nih.gov/pubmed/19948208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2009.11.016
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