Nonlinearity between action potential alternans and restitution, which both predict ventricular arrhythmic properties in Scn5a(+/−) and wild-type murine hearts

Electrocardiographic QT- and T-wave alternans, presaging ventricular arrhythmia, reflects compromised adaptation of action potential (AP) duration (APD) to altered heart rate, classically attributed to incomplete Na(v)1.5 channel recovery prior to subsequent stimulation. The restitution hypothesis s...

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Detaylı Bibliyografya
Asıl Yazarlar: Matthews, Gareth D. K., Guzadhur, Laila, Grace, Andrew, Huang, Christopher L-H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2012
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3379158/
https://ncbi.nlm.nih.gov/pubmed/22461438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00039.2012
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