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Comparing the Folding and Misfolding Energy Landscapes of Phosphoglycerate Kinase
Partitioning of polypeptides between protein folding and amyloid formation is of outstanding pathophysiological importance. Using yeast phosphoglycerate kinase as model, here we identify the features of the energy landscape that decide the fate of the protein: folding or amyloidogenesis. Structure f...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3379013/ https://ncbi.nlm.nih.gov/pubmed/22735533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.05.006 |
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