Prebiotically plausible mechanisms increase compositional diversity of nucleic acid sequences

During the origin of life, the biological information of nucleic acid polymers must have increased to encode functional molecules (the RNA world). Ribozymes tend to be compositionally unbiased, as is the vast majority of possible sequence space. However, ribonucleotides vary greatly in synthetic yie...

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Библиографические подробности
Главные авторы: Derr, Julien, Manapat, Michael L., Rajamani, Sudha, Leu, Kevin, Xulvi-Brunet, Ramon, Joseph, Isaac, Nowak, Martin A., Chen, Irene A.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2012
Предметы:
Synthetic Biology and Chemistry
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378899/
https://ncbi.nlm.nih.gov/pubmed/22319215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks065
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