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Prebiotically plausible mechanisms increase compositional diversity of nucleic acid sequences

During the origin of life, the biological information of nucleic acid polymers must have increased to encode functional molecules (the RNA world). Ribozymes tend to be compositionally unbiased, as is the vast majority of possible sequence space. However, ribonucleotides vary greatly in synthetic yie...

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Detalhes bibliográficos
Main Authors: Derr, Julien, Manapat, Michael L., Rajamani, Sudha, Leu, Kevin, Xulvi-Brunet, Ramon, Joseph, Isaac, Nowak, Martin A., Chen, Irene A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378899/
https://ncbi.nlm.nih.gov/pubmed/22319215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks065
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