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Differential expression analysis of multifactor RNA-Seq experiments with respect to biological variation

A flexible statistical framework is developed for the analysis of read counts from RNA-Seq gene expression studies. It provides the ability to analyse complex experiments involving multiple treatment conditions and blocking variables while still taking full account of biological variation. Biologica...

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Detalhes bibliográficos
Main Authors: McCarthy, Davis J., Chen, Yunshun, Smyth, Gordon K.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378882/
https://ncbi.nlm.nih.gov/pubmed/22287627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks042
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