Fidelity of tRNA 5′-maturation: a possible basis for the functional dependence of archaeal and eukaryal RNase P on multiple protein cofactors

RNase P, which catalyzes tRNA 5′-maturation, typically comprises a catalytic RNase P RNA (RPR) and a varying number of RNase P proteins (RPPs): 1 in bacteria, at least 4 in archaea and 9 in eukarya. The four archaeal RPPs have eukaryotic homologs and function as heterodimers (POP5•RPP30 and RPP21•RP...

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Bibliographische Detailangaben
Hauptverfasser: Chen, Wen-Yi, Singh, Deepali, Lai, Lien B., Stiffler, Michael A., Lai, Hue D., Foster, Mark P., Gopalan, Venkat
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2012
Schlagworte:
RNA
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378863/
https://ncbi.nlm.nih.gov/pubmed/22298511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks013
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