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Preclinical rationale for use of the clinically-available multitargeted tyrosine kinase inhibitor crizotinib in ROS1 translocated lung cancer
HYPOTHESIS: Most clinically-available small molecule kinase inhibitors are multitargeted and can inhibit multiple kinases. Our driving hypothesis was that one of these multitargeted tyrosine kinase inhibitors (TKIs) would have anti-proliferative activity against ROS1 translocated non-small-cell lung...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3378824/ https://ncbi.nlm.nih.gov/pubmed/22617245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0b013e3182570919 |
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