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Simultaneous measurement of insulin sensitivity, insulin secretion and the disposition index in conscious unhandled mice

Of the parameters that determine glucose disposal and progression to diabetes in humans: first-phase insulin secretion, glucose effectiveness, insulin sensitivity, and the disposition index, only insulin sensitivity can be reliably measured in conscious mice. To determine the importance of the other...

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Détails bibliographiques
Auteurs principaux: Alonso, L. C., Watanabe, Y., Stefanovski, D., Lee, E. J., Singamsetty, S., Romano, L. C., Zou, B., Garcia-Ocana, A., Bergman, R. N., O’Donnell, C. P.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378770/
https://ncbi.nlm.nih.gov/pubmed/22331130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oby.2012.36
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