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Adult-onset focal expression of mutated human tau in the hippocampus impairs spatial working memory of rats

Tauopathy in the hippocampus is one of the earliest cardinal features of Alzheimer’s disease (AD), a condition characterized by progressive memory impairments. In fact, density of tau neurofibrillary tangles (NFTs) in the hippocampus strongly correlates with severity of cognitive impairments in AD....

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Bibliografske podrobnosti
Main Authors: Mustroph, M.L., King, M.A., Klein, R.L., Ramirez, J.J.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378764/
https://ncbi.nlm.nih.gov/pubmed/22561128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2012.04.034
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