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Adult-onset focal expression of mutated human tau in the hippocampus impairs spatial working memory of rats
Tauopathy in the hippocampus is one of the earliest cardinal features of Alzheimer’s disease (AD), a condition characterized by progressive memory impairments. In fact, density of tau neurofibrillary tangles (NFTs) in the hippocampus strongly correlates with severity of cognitive impairments in AD....
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3378764/ https://ncbi.nlm.nih.gov/pubmed/22561128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2012.04.034 |
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