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Nuclear noncoding RNA surveillance: is the end in sight?

Nuclear noncoding RNA (ncRNA) surveillance pathways play key roles in shaping the steady-state transcriptomes of eukaryotic cells. Defective and unneeded ncRNAs are primarily degraded by exoribonucleases that rely on protein cofactors to identify these RNAs. Recent studies have begun to elucidate bo...

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Hlavní autoři: Wolin, Sandra L., Sim, Soyeong, Chen, Xinguo
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378728/
https://ncbi.nlm.nih.gov/pubmed/22475369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2012.03.005
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