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Noncoding RNA surveillance: The ends justify the means

Numerous surveillance pathways sculpt eukaryotic transcriptomes by degrading unneeded, defective and potentially harmful noncoding RNAs (ncRNAs). Because aberrant and excess ncRNAs are largely degraded by exoribonucleases, a key characteristic of these RNAs is an accessible, protein-free 5’ or 3’ en...

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Bibliografiske detaljer
Udgivet i:Chem Rev
Main Authors: Belair, Cedric, Sim, Soyeong, Wolin, Sandra L.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8071604/
https://ncbi.nlm.nih.gov/pubmed/29023106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrev.7b00462
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