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Noncoding RNA surveillance: The ends justify the means

Numerous surveillance pathways sculpt eukaryotic transcriptomes by degrading unneeded, defective and potentially harmful noncoding RNAs (ncRNAs). Because aberrant and excess ncRNAs are largely degraded by exoribonucleases, a key characteristic of these RNAs is an accessible, protein-free 5’ or 3’ en...

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Bibliographic Details
Published in:Chem Rev
Main Authors: Belair, Cedric, Sim, Soyeong, Wolin, Sandra L.
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8071604/
https://ncbi.nlm.nih.gov/pubmed/29023106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrev.7b00462
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