Prediction of Warfarin Dose Reductions in Puerto Rican Patients, Based on Combinatorial CYP2C9 and VKORC1 Genotypes

BACKGROUND: The influence of CYP2C9 and VKORC1 polymorphisms on warfarin dose has been investigated in white, Asian, and African American populations but not in Puerto Rican Hispanic patients. OBJECTIVE: To test the associations between genotypes, international normalized ratio (INR) measurements, a...

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Main Authors: Valentin, Isa Ivette, Vazquez, Joan, Rivera-Miranda, Giselle, Seip, Richard L, Velez, Meredith, Kocherla, Mohan, Bogaard, Kali, Cruz-Gonzalez, Iadelisse, Cadilla, Carmen L, Renta, Jessica Y, Felliu, Juan F, Ramos, Alga S, Alejandro-Cowan, Yirelia, Gorowski, Krystyna, Ruaño, Gualberto, Duconge, Jorge
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378722/
https://ncbi.nlm.nih.gov/pubmed/22274142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1345/aph.1Q190
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