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Lack of a p21(waf1/cip)-Dependent G1/S Checkpoint in Neural Stem and Progenitor Cells After DNA Damage In Vivo
The cyclin-dependent kinase inhibitor p21(waf1/cip) mediates the p53-dependent G1/S checkpoint, which is generally considered to be a critical requirement to maintain genomic stability after DNA damage. We used staggered 5-ethynyl-2′deoxyuridine/5-bromo-2′-deoxyuridine double-labeling in vivo to inv...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Wiley Subscription Services, Inc., A Wiley Company
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3378718/ https://ncbi.nlm.nih.gov/pubmed/22162343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1010 |
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