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Role of Hedgehog signalling at the transition from double-positive to single-positive thymocyte
In the thymus, developing T cells receive signals that determine lineage choice, specificity, MHC restriction and tolerance to self-antigen. One way in which thymocytes receive instruction is by secretion of Sonic hedgehog (Shh) from thymic epithelial cells. We have previously shown that Hedgehog (H...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
WILEY-VCH Verlag
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3378705/ https://ncbi.nlm.nih.gov/pubmed/22101858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201141758 |
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