Arginine depletion as a mechanism for the immune privilege of corneal allografts

The cornea is an immune privileged tissue. Since arginase has been found to modulate T-cell function by depleting arginine, we investigated the expression of arginase in the cornea and its possible role in immune privilege using a murine transplant model. We found that both the endothelium and epith...

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Bibliographische Detailangaben
Hauptverfasser: Fu, Hongmei, Khan, Adnan, Coe, David, Zaher, Sarah, Chai, Jian-Guo, Kropf, Pascale, Müller, Ingrid, Larkin, Daniel F P, George, Andrew J T
Format: Artigo
Sprache:Inglês
Veröffentlicht: WILEY-VCH Verlag 2011
Schlagworte:
Immunomodulation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378701/
https://ncbi.nlm.nih.gov/pubmed/21805470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201141683
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