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Genomic evidence of pre-invasive clonal expansion, dispersal and progression in bronchial dysplasia

The term ‘field cancerization’ is used to describe an epithelial surface that has a propensity to develop cancerous lesions, and in the case of the aerodigestive tract this is often as a result of chronic exposure to carcinogens in cigarette smoke 1, 2. The clinical endpoint is the development of mu...

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Detalhes bibliográficos
Main Authors: McCaughan, Frank, Pipinikas, Christodoulos P, Janes, Sam M, George, P Jeremy, Rabbitts, Pamela H, Dear, Paul H
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd. 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378694/
https://ncbi.nlm.nih.gov/pubmed/21506132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.2887
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