Genome-Wide Screen for Metabolic Syndrome Susceptibility Loci Reveals Strong Lipid Gene Contribution but No Evidence for Common Genetic Basis for Clustering of Metabolic Syndrome Traits

BACKGROUND: Genome-wide association (GWA) studies have identified several susceptibility loci for metabolic syndrome (MetS) component traits, but have had variable success in identifying susceptibility loci to the syndrome as an entity. We conducted a GWA study on MetS and its component traits in fo...

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Bibliografski detalji
Glavni autori: Kristiansson, Kati, Perola, Markus, Tikkanen, Emmi, Kettunen, Johannes, Surakka, Ida, Havulinna, Aki S., Stančáková, Alena, Barnes, Chris, Widen, Elisabeth, Kajantie, Eero, Eriksson, Johan G., Viikari, Jorma, Kähönen, Mika, Lehtimäki, Terho, Raitakari, Olli T., Hartikainen, Anna-Liisa, Ruokonen, Aimo, Pouta, Anneli, Jula, Antti, Kangas, Antti J., Soininen, Pasi, Ala-Korpela, Mika, Männistö, Satu, Jousilahti, Pekka, Bonnycastle, Lori L., Järvelin, Marjo-Riitta, Kuusisto, Johanna, Collins, Francis S., Laakso, Markku, Hurles, Matthew E., Palotie, Aarno, Peltonen, Leena, Ripatti, Samuli, Salomaa, Veikko
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378651/
https://ncbi.nlm.nih.gov/pubmed/22399527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.111.961482
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