Genome-Wide Screen for Metabolic Syndrome Susceptibility Loci Reveals Strong Lipid Gene Contribution but No Evidence for Common Genetic Basis for Clustering of Metabolic Syndrome Traits

BACKGROUND: Genome-wide association (GWA) studies have identified several susceptibility loci for metabolic syndrome (MetS) component traits, but have had variable success in identifying susceptibility loci to the syndrome as an entity. We conducted a GWA study on MetS and its component traits in fo...

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Detalhes bibliográficos
Main Authors: Kristiansson, Kati, Perola, Markus, Tikkanen, Emmi, Kettunen, Johannes, Surakka, Ida, Havulinna, Aki S., Stančáková, Alena, Barnes, Chris, Widen, Elisabeth, Kajantie, Eero, Eriksson, Johan G., Viikari, Jorma, Kähönen, Mika, Lehtimäki, Terho, Raitakari, Olli T., Hartikainen, Anna-Liisa, Ruokonen, Aimo, Pouta, Anneli, Jula, Antti, Kangas, Antti J., Soininen, Pasi, Ala-Korpela, Mika, Männistö, Satu, Jousilahti, Pekka, Bonnycastle, Lori L., Järvelin, Marjo-Riitta, Kuusisto, Johanna, Collins, Francis S., Laakso, Markku, Hurles, Matthew E., Palotie, Aarno, Peltonen, Leena, Ripatti, Samuli, Salomaa, Veikko
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378651/
https://ncbi.nlm.nih.gov/pubmed/22399527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.111.961482
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