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Overexpression of wild-type or mutants forms of CEBPA alter normal human hematopoiesis
C/EBPα (CEBPA) is mutated in approximately 8 % of AML in both familial and sporadic AML and, with FLT3 and NPM1, has received most attention as a predictive marker of outcome in patients with normal karyotype disease. Mutations clustering to either the N- or C-terminal (N-and C-ter) portions of the...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3378638/ https://ncbi.nlm.nih.gov/pubmed/22371011 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2012.38 |
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