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Maintenance of T cell function in the face of chronic antigen stimulation and repeated reactivation for a latent virus infection()

Persisting infections are often associated with chronic T cell activation. For certain pathogens, this can lead to T cell exhaustion and survival of what is otherwise a cleared infection. In contrast, for herpesviruses, T cells never eliminate infection once it is established. Instead, effective imm...

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Main Authors: Mackay, Laura K., Wakim, Linda, van Vliet, Catherine J., Jones, Claerwen M., Mueller, Scott N., Bannard, Oliver, Fearon, Douglas T., Heath, William R., Carbone, Francis R.
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378511/
https://ncbi.nlm.nih.gov/pubmed/22271651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102719
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