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Ras trafficking, localization and compartmentalized signalling
Ras proteins are proto-oncogenes that are frequently mutated in human cancers. Three closely related isoforms, HRAS, KRAS and NRAS, are expressed in all cells and have overlapping but distinctive functions. Recent work has revealed how differences between the Ras isoforms in their trafficking, local...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3378476/ https://ncbi.nlm.nih.gov/pubmed/21924373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2011.09.002 |
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