NADPH oxidase inhibition reduces tubular sodium transport and improves kidney oxygenation in diabetes

Sustained hyperglycemia is associated with increased oxidative stress resulting in decreased intrarenal oxygen tension (Po(2)) due to increased oxygen consumption (Qo(2)). Chronic blockade of the main superoxide radicals producing system, the nicotinamide adenine dinucleotide phosphate (NADPH) oxida...

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Bibliographic Details
Main Authors: Persson, Patrik, Hansell, Peter, Palm, Fredrik
Format: Artigo
Language:Inglês
Published: American Physiological Society 2012
Subjects:
Fluid and Electrolyte Homeostasis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378341/
https://ncbi.nlm.nih.gov/pubmed/22552796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00502.2011
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