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NADPH oxidase inhibition reduces tubular sodium transport and improves kidney oxygenation in diabetes

Sustained hyperglycemia is associated with increased oxidative stress resulting in decreased intrarenal oxygen tension (Po(2)) due to increased oxygen consumption (Qo(2)). Chronic blockade of the main superoxide radicals producing system, the nicotinamide adenine dinucleotide phosphate (NADPH) oxida...

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Detalhes bibliográficos
Main Authors: Persson, Patrik, Hansell, Peter, Palm, Fredrik
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378341/
https://ncbi.nlm.nih.gov/pubmed/22552796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00502.2011
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