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The Alternatively Spliced Acid Box Region Plays a Key Role in FGF Receptor Autoinhibition
Uncontrolled fibroblast growth factor (FGF) signaling can lead to human malignancies necessitating multiple layers of self-regulatory control mechanisms. Fibroblast growth factor receptor (FGFR) autoinhibition mediated by the alternatively spliced immunoglobulin (Ig) domain 1 (D1) and the acid box (...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3378326/ https://ncbi.nlm.nih.gov/pubmed/22244757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2011.10.022 |
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