The Alternatively Spliced Acid Box Region Plays a Key Role in FGF Receptor Autoinhibition

Uncontrolled fibroblast growth factor (FGF) signaling can lead to human malignancies necessitating multiple layers of self-regulatory control mechanisms. Fibroblast growth factor receptor (FGFR) autoinhibition mediated by the alternatively spliced immunoglobulin (Ig) domain 1 (D1) and the acid box (...

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Autori principali: Kalinina, Juliya, Dutta, Kaushik, Ilghari, Dariush, Beenken, Andrew, Goetz, Regina, Eliseenkova, Anna V., Cowburn, David, Mohammadi, Moosa
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378326/
https://ncbi.nlm.nih.gov/pubmed/22244757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2011.10.022
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