PEG-albumin supraplasma expansion is due to increased vessel wall shear stress induced by blood viscosity shear thinning

We studied the extreme hemodilution to a hematocrit of 11% induced by three plasma expanders: polyethylene glycol (PEG)-conjugated albumin (PEG-Alb), 6% 70-kDa dextran, and 6% 500-kDa dextran. The experimental component of our study relied on microelectrodes and cardiac output to measure both the rh...

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Главные авторы: Sriram, Krishna, Tsai, Amy G., Cabrales, Pedro, Meng, Fantao, Acharya, Seetharama A., Tartakovsky, Daniel M., Intaglietta, Marcos
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2012
Предметы:
Vascular Biology and Microcirculation
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378262/
https://ncbi.nlm.nih.gov/pubmed/22505638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01090.2011
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