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Downregulation of the CCK-B receptor in pancreatic cancer cells blocks proliferation and promotes apoptosis
Gastrin stimulates the growth of pancreatic cancer cells through the activation of the cholecystokinin-B receptor (CCK-BR), which has been found to be overexpressed in pancreatic cancer. In this study, we proposed that the CCK-BR drives growth of pancreatic cancer; hence, interruption of CCK-BR acti...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3378167/ https://ncbi.nlm.nih.gov/pubmed/22442157 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00460.2011 |
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