c-Jun/AP-1 is required for CCK-induced pancreatic acinar cell dedifferentiation and DNA synthesis in vitro

Endogenous CCK plays an important role in pancreatic regeneration after pancreatitis. We used primary culture of mouse pancreatic acinar cells to evaluate the effect of CCK on acinar cell morphology and gene expression and to determine signaling pathways required for proliferation of acinar cells in...

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Bibliographic Details
Main Authors: Guo, Lili, Sans, Maria Dolors, Hou, Yanan, Ernst, Stephen A., Williams, John A.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2012
Subjects:
Hormones and Signaling
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378092/
https://ncbi.nlm.nih.gov/pubmed/22461029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00129.2010
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