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Retinoid Content, Visual Responses, and Ocular Morphology Are Compromised in the Retinas of Mice Lacking the Retinol-Binding Protein Receptor, STRA6

PURPOSE. We report generation of a mouse model in which the STRA6 gene has been disrupted functionally to facilitate the study of visual responses, changes in ocular morphology, and retinoid processing under STRA6 protein deficiency. METHODS. A null mouse line, stra6 −/−, was generated. Western Blot...

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Detalhes bibliográficos
Main Authors: Ruiz, Alberto, Mark, Manuel, Jacobs, Hugues, Klopfenstein, Muriel, Hu, Jane, Lloyd, Marcia, Habib, Samer, Tosha, Chinatsu, Radu, Roxana A, Ghyselinck, Norbert B, Nusinowitz, Steven, Bok, Dean
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378086/
https://ncbi.nlm.nih.gov/pubmed/22467576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-8476
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