Mitochondrial DNA That Escapes from Autophagy Causes Inflammation and Heart Failure

Heart failure is a leading cause of morbidity and mortality in industrialized countries. Although infection with microorganisms is not involved in the development of heart failure in most cases, inflammation has been implicated in the pathogenesis of heart failure(1). However, the mechanisms respons...

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Bibliographic Details
Main Authors: Oka, Takafumi, Hikoso, Shungo, Yamaguchi, Osamu, Taneike, Manabu, Takeda, Toshihiro, Tamai, Takahito, Oyabu, Jota, Murakawa, Tomokazu, Nakayama, Hiroyuki, Nishida, Kazuhiko, Akira, Shizuo, Yamamoto, Akitsugu, Komuro, Issei, Otsu, Kinya
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378041/
https://ncbi.nlm.nih.gov/pubmed/22535248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10992
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