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A Low-Cost Exon Capture Method Suitable for Large-Scale Screening of Genetic Deafness by the Massively-Parallel Sequencing Approach

Current major barriers for using next-generation sequencing (NGS) technologies in genetic mutation screening on an epidemiological scale appear to be the high accuracy demanded by clinical applications and high per-sample cost. How to achieve high efficiency in enriching targeted disease genes while...

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Autors principals: Tang, Wenxue, Qian, Dong, Ahmad, Shoeb, Mattox, Douglas, Todd, N. Wendell, Han, Harrison, Huang, Shouting, Li, Yuhua, Wang, Yunfeng, Li, Huawei, Lin, Xi
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378026/
https://ncbi.nlm.nih.gov/pubmed/22480152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/gtmb.2011.0187
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